Pain Relievers

Zapain 30MG / 500MG Codeine: Effective Relief for Moderate to Severe Pain

What Is Zapain?

Zapain is a prescription painkiller that combines two active ingredients: codeine phosphate (30mg) and paracetamol (500mg). Together, they work as a dual-action treatment to help relieve moderate to severe pain when regular painkillers, like paracetamol or ibuprofen alone, aren’t strong enough.

It’s commonly prescribed for post-operative pain, injuries, dental procedures, or chronic conditions like arthritis.

Zapain tablets

How Does Zapain Work?

Zapain tackles pain from two angles:

  • Paracetamol reduces pain and brings down fever by blocking pain signals in the brain.
  • Codeine is a mild opioid that transforms into morphine in the body, working on the central nervous system to dull the brain’s response to pain.

The result? More effective pain relief than taking either drug on its own.

When Is Zapain Used?

Doctors usually prescribe Zapain for:

  • Post-surgery recovery
  • Severe toothache
  • Back pain or sciatica
  • Muscle strains or joint inflammation
  • Migraine (when paracetamol alone isn’t enough)
  • Pain that doesn’t respond to over-the-counter painkillers

It’s typically used short-term, to manage pain flare-ups that need extra support.

How to Take Zapain Tablets

  • Take 1–2 tablets every 4–6 hours, as needed
  • Do not exceed 8 tablets in 24 hours
  • Always swallow tablets whole with water
  • Take with food to reduce the risk of nausea

Never take other products containing paracetamol while on Zapain—you could accidentally overdose on paracetamol, which can be dangerous.

How Long Does It Take to Work?

Zapain typically starts working within 30 to 60 minutes. You’ll feel reduced pain and more comfort as the medication gets absorbed into your system.

Its effects usually last for around 4–6 hours.

Side Effects of Zapain

Like all medications, Zapain can cause side effects. Most are mild and manageable.

Common ones include:

  • Drowsiness or sleepiness
  • Nausea or vomiting
  • Constipation
  • Dizziness or light-headedness
  • Dry mouth

To manage constipation, drink lots of water, eat high-fibre foods, and consider a stool softener if needed.

Serious Side Effects (Seek Help If You Notice These)

  • Breathing difficulties
  • Allergic reactions like rash, swelling, or itching
  • Yellowing of the skin or eyes (could signal liver issues)
  • Confusion or hallucinations
  • Unusual tiredness or dark urine

If any of these occur, stop taking Zapain and contact your doctor immediately.

Is Zapain Addictive?

Yes, codeine is an opioid, and there’s a risk of dependence, especially with long-term or high-dose use. That’s why Zapain is usually prescribed for short-term pain only, under close supervision.

Signs of dependence may include:

  • Feeling you need to take it more often
  • Withdrawal symptoms if you miss a dose
  • Craving the medication even when pain is gone

Always follow your doctor’s instructions carefully, and don’t suddenly stop if you’ve been on it for a while—tapering is safer.

Can You Drive on Zapain?

Not safely—at least not at first. Zapain may cause drowsiness, blurred vision, or delayed reaction times, especially in the first few doses.

If you feel sleepy or “foggy,” don’t drive or operate machinery. Wait until you know how your body reacts.

What Happens If You Miss a Dose?

If you miss a dose, take it as soon as you remember—unless it’s almost time for your next dose. Never double up.

Stick to your schedule, and use reminders if needed.

What to Avoid While Taking Zapain

  • Alcohol – increases the risk of drowsiness, liver damage, and breathing issues
  • Other paracetamol products – raises the risk of liver toxicity
  • Other opioids or sedatives – may cause severe drowsiness or overdose

Always check labels or ask a pharmacist if you’re unsure.


How long can I take Zapain safely?
Zapain is usually safe for short-term use (a few days to a week). Long-term use increases the risk of dependence and side effects. Always follow your doctor’s advice.

Can I take Zapain with ibuprofen?
Yes, Zapain can be taken with ibuprofen if extra pain relief is needed, as long as you’re not allergic or sensitive to either. Just avoid doubling up on paracetamol.

Is it safe to take Zapain before bed?
Yes, many people take Zapain at night for pain relief and better sleep. It may cause drowsiness, so don’t plan on staying active after taking it.

Can I stop Zapain suddenly after a week?
If you’ve been taking it for a short time, stopping suddenly is usually fine. If you’ve been on it daily for more than a couple of weeks, taper slowly under medical supervision.

Is Zapain stronger than co-codamol?
Yes—Zapain contains 30mg of codeine, which is a higher dose than standard co-codamol (which usually contains 8mg or 15mg of codeine). It’s generally used for stronger pain.